Madden 25 Week 7 NFL Simulation

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San Francisco 49ers @ Tennessee Titans

Colin Kaepernick threw for 412 yards and five touchdowns as the 49ers pummeled the Titans in Nashville.

There isn’t much more to say than this was an old fashion whooping. The 49ers defense sacked Tennessee QB Ryan Fitzpatrick 11 times and picked him off four in the dominating win. That alone was why San Francisco coasted throughout much of this one.